sideroblast
Học thuậtThân thiện
Definition
Noun: A sideroblast is an immature red blood cell (an erythroblast) that contains granules of ferritin, an iron-storage protein, within its cytoplasm.
Usage
The term is used specifically in the fields of hematology and medicine to describe a particular stage or condition of red blood cell development. * The bone marrow biopsy revealed the presence of sideroblasts. * Ring sideroblasts are a key diagnostic feature in certain types of anemia.
Advanced Usage
- Ring Sideroblast: A pathological type of sideroblast where iron-laden mitochondria form a ring around the nucleus. This is a hallmark of certain myelodysplastic syndromes.
- The identification of ring sideroblasts is crucial for diagnosing myelodysplastic syndrome with ring sideroblasts (MDS-RS).
Variants and Related Words
- Sideroblastic (adjective): Pertaining to or characterized by sideroblasts.
- The patient was diagnosed with sideroblastic anemia.
Synonyms
- None that are exact. It is a specific histological term.
Different Meanings
This word has only one specific, technical meaning in medical science.
Noun
- an erythroblast having granules of ferritin