glutamic oxalacetic transaminase
Definition
- Noun:
- An enzyme involved in transamination: Glutamic oxalacetic transaminase is a specific enzyme that catalyzes a transamination reaction, transferring an amino group between aspartate and alpha-ketoglutarate. It is also commonly known by the abbreviation GOT and is now more formally called aspartate transaminase (AST).
Usage Examples
- Noun:
- Elevated levels of glutamic oxalacetic transaminase in the blood can indicate liver damage.
- The laboratory test measured the activity of glutamic oxalacetic transaminase.
Advanced Usage
- Clinical Context: The term is primarily used in medical and biochemical contexts, especially in diagnosing and monitoring conditions like myocardial infarction or hepatitis.
- The doctor ordered a test for serum glutamic oxalacetic transaminase to assess the patient's cardiac health.
Variants and Related Words
- Aspartate transaminase (AST): The modern, more precise name for the same enzyme.
- Serum glutamic-oxaloacetic transaminase (SGOT): The term used when referring to the enzyme's level measured in blood serum.
- Transaminase: The general class of enzymes to which it belongs.
Synonyms
- Aspartate aminotransferase: The systematic synonym.
- AST: The common acronym.
- GOT: The older acronym.
Related Phrases
- SGOT test: A common blood test panel that includes measurement of this enzyme.
- The SGOT test is part of a standard liver function panel.
Noun
-
an enzyme involved in transamination
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