haemoglobinemia
Học thuậtThân thiện
Definition
Noun: - A medical condition characterized by the abnormal presence of hemoglobin in the blood plasma. Hemoglobin, which normally resides inside red blood cells, is found freely circulating in the liquid part of the blood.
Usage
The term is used in medical and clinical contexts to describe a specific laboratory finding or symptom of an underlying disorder. It indicates that red blood cells are breaking down (hemolyzing) and releasing their contents into the bloodstream. - The patient's haemoglobinemia was a clear indicator of severe hemolysis. - Laboratory tests confirmed haemoglobinemia, prompting further investigation into the cause.
Advanced Usage
- Pathophysiological Context: Haemoglobinemia is not a disease itself but a sign of intravascular hemolysis, which can be caused by conditions such as paroxysmal nocturnal hemoglobinuria, severe burns, certain infections, or incompatible blood transfusions.
- Diagnostic Significance: Its presence often leads to other sequelae, such as haemoglobinuria (hemoglobin in the urine), which gives urine a dark red or cola-colored appearance.
Variants and Related Words
- Hemoglobinemia: The American English spelling of the same term.
- Hemolysis (n): The process of red blood cell destruction that leads to haemoglobinemia.
- Haemoglobinuria (n): The presence of hemoglobin in the urine, a common consequence of haemoglobinemia.
- Hyperhaemoglobinemia (n): An excessive amount of hemoglobin in the blood plasma.
Synonyms
- Free hemoglobin in plasma: A descriptive synonym.
- Intravascular hemolysis: The process causing the condition, often used in related contexts.
Noun
- presence of excessive hemoglobin in the blood plasma