hemoglobinemia
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Definition
- Noun:
- A medical condition characterized by an abnormally high concentration of hemoglobin in the blood plasma: Hemoglobinemia refers to the presence of free hemoglobin in the liquid part of the blood (plasma), which is outside of the red blood cells where it normally resides.
Usage
- Hemoglobinemia is a clinical finding, not a disease itself, but a sign of an underlying condition causing the destruction of red blood cells (hemolysis).
- It is typically diagnosed through laboratory blood tests.
- The condition can lead to complications if the released hemoglobin is excessive.
Examples
- The patient's symptoms and lab results, including pink-tinged plasma, were consistent with hemoglobinemia.
- Severe malaria can cause massive hemolysis, resulting in hemoglobinemia and hemoglobinuria (hemoglobin in the urine).
- The doctor ordered tests to check for hemoglobinemia after the patient presented with jaundice and dark urine.
Advanced Usage
- "Intravascular hemoglobinemia": Specifies that the hemoglobin is released directly into the bloodstream due to red blood cell destruction within the blood vessels.
- Paroxysmal nocturnal hemoglobinuria (PNH) causes chronic intravascular hemoglobinemia.
Variants and Related Words
- Hemoglobin (n): The iron-containing protein in red blood cells that carries oxygen.
- Hemoglobinuria (n): The presence of hemoglobin in the urine, often occurring concurrently with hemoglobinemia.
- Hyperhemoglobinemia (n): An alternative term emphasizing the excessive (hyper) level of hemoglobin in plasma.
- Hemolysis (n): The destruction of red blood cells, which is the primary cause of hemoglobinemia.
Synonyms
- Hyperhemoglobinemia (n): Presence of excessive hemoglobin in blood plasma.
- Haemoglobinaemia (n): The British English spelling variant.
Notes
- Hemoglobinemia is distinct from polycythemia, which is an increase in the total number of red blood cells and the hemoglobin contained within them. Hemoglobinemia involves hemoglobin of the cells.
- It is a key indicator of intravascular hemolysis.
Noun
- presence of excessive hemoglobin in the blood plasma