hemosiderosis

Thân thiện

A doctor points to hemosiderosis on a medical slide during a lecture.

Definition

1. Noun:
   • A pathological condition characterized by the abnormal accumulation of the iron-storage complex hemosiderin in body tissues: Hemosiderosis is a disorder involving excessive iron deposition, typically within cells of the reticuloendothelial system (e.g., in the liver, spleen, bone marrow). It is often a secondary condition resulting from other diseases.

Usage

• Hemosiderosis is primarily used in medical and clinical contexts to describe a state of iron overload that is distinct from, though sometimes related to, hemochromatosis.
• It is typically discussed as a finding or symptom of an underlying condition rather than as a primary disease itself.

Examples

• Noun:
  • The patient's chronic blood transfusions led to the development of transfusion hemosiderosis.
  • Pulmonary hemosiderosis can result in coughing up blood.
  • The biopsy confirmed hemosiderosis in the liver tissue.

Advanced Usage

• "Secondary hemosiderosis": Specifies iron overload that occurs as a consequence of another condition, such as chronic hemolytic anemias or frequent blood transfusions.

  • Secondary hemosiderosis is a major concern in the long-term management of thalassemia patients.

• "Idiopathic pulmonary hemosiderosis": Refers to a rare condition of recurrent bleeding into the lungs leading to iron accumulation, where the cause is unknown.

  • The child was diagnosed with idiopathic pulmonary hemosiderosis.

Variants and Related Words

• Hemosiderin (n): The iron-protein complex that accumulates in tissues in hemosiderosis.

  • Macrophages filled with hemosiderin are a hallmark of the condition.

• Hemochromatosis (n): A related but often more severe genetic disorder of systemic iron overload, where iron accumulates in parenchymal cells of organs, causing damage.

  • Unlike hemosiderosis, hemochromatosis involves toxic iron accumulation in organ cells.

Synonyms

• Iron overload: A broader, more general term for excessive iron in the body.
• Siderosis: A term sometimes used interchangeably with hemosiderosis, particularly in the context of the lungs (pulmonary siderosis).

Related Phrases

• Transfusion hemosiderosis: A specific type caused by multiple blood transfusions.

  • Chelation therapy is used to manage transfusion hemosiderosis.

• Hemosiderin deposition: The process or result of hemosiderin building up in tissues.

  • The MRI showed significant hemosiderin deposition in the spleen.

Học thuật

Noun

1. abnormal deposit of hemosiderin; often a symptom of thalassemia or hemochromatosis

Từ đồng nghĩa

• haemosiderosis