hemosiderosis
- Noun:
- A pathological condition characterized by the abnormal accumulation of the iron-storage complex hemosiderin in body tissues: Hemosiderosis is a disorder involving excessive iron deposition, typically within cells of the reticuloendothelial system (e.g., in the liver, spleen, bone marrow). It is often a secondary condition resulting from other diseases.
- Hemosiderosis is primarily used in medical and clinical contexts to describe a state of iron overload that is distinct from, though sometimes related to, hemochromatosis.
- It is typically discussed as a finding or symptom of an underlying condition rather than as a primary disease itself.
- Noun:
- The patient's chronic blood transfusions led to the development of transfusion hemosiderosis.
- Pulmonary hemosiderosis can result in coughing up blood.
- The biopsy confirmed hemosiderosis in the liver tissue.
"Secondary hemosiderosis": Specifies iron overload that occurs as a consequence of another condition, such as chronic hemolytic anemias or frequent blood transfusions.
- Secondary hemosiderosis is a major concern in the long-term management of thalassemia patients.
"Idiopathic pulmonary hemosiderosis": Refers to a rare condition of recurrent bleeding into the lungs leading to iron accumulation, where the cause is unknown.
- The child was diagnosed with idiopathic pulmonary hemosiderosis.
Hemosiderin (n): The iron-protein complex that accumulates in tissues in hemosiderosis.
- Macrophages filled with hemosiderin are a hallmark of the condition.
Hemochromatosis (n): A related but often more severe genetic disorder of systemic iron overload, where iron accumulates in parenchymal cells of organs, causing damage.
- Unlike hemosiderosis, hemochromatosis involves toxic iron accumulation in organ cells.
- Iron overload: A broader, more general term for excessive iron in the body.
- Siderosis: A term sometimes used interchangeably with hemosiderosis, particularly in the context of the lungs (pulmonary siderosis).
Transfusion hemosiderosis: A specific type caused by multiple blood transfusions.
- Chelation therapy is used to manage transfusion hemosiderosis.
Hemosiderin deposition: The process or result of hemosiderin building up in tissues.
- The MRI showed significant hemosiderin deposition in the spleen.
-
abnormal deposit of hemosiderin; often a symptom of thalassemia or hemochromatosis
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