Definition

Noun: A state in which the immune system's ability to fight infectious disease and other threats is compromised or entirely absent. It is characterized by an inadequate or defective function in some part of the body's immune system, leading to reduced resistance and increased susceptibility to infections and certain cancers.

Usage

The term "immunodeficiency" is used to describe a medical condition, either inherited (primary) or acquired (secondary). It is a formal, clinical term. * The patient was diagnosed with a severe immunodeficiency. * Immunodeficiency can result from genetic defects, viral infections like HIV, or certain medical treatments.

Examples

• Primary immunodeficiency disorders are often present from birth.
• HIV infection leads to acquired immunodeficiency syndrome (AIDS).
• The drug's side effects included temporary immunodeficiency.
• Researchers are studying new therapies for combined immunodeficiency.

Advanced Usage

• "To have an immunodeficiency": This is the standard phrasing to indicate someone is affected by this condition.
  • Because he has an immunodeficiency, he must be very careful to avoid infections.
• The term is central to the name of the disease Acquired Immunodeficiency Syndrome (AIDS).

Variants and Related Words

• Immunodeficient (adjective): Having an immunodeficiency.
  • The immunodeficient child required a protective environment.
• Immunocompromised (adjective): A broader, often synonymous term for having a weakened immune system, which can include but is not limited to immunodeficiency states.

Synonyms

• Immune deficiency
• Impaired immunity
• Weakened immune system (less clinical)

Antonyms

• Immunocompetence
• Robust immunity

Noun

1. immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced