Definition

1. Noun:
   • A monoclonal antibody medication: Infliximab is a pharmaceutical drug that belongs to a class of biological agents known as anti-TNF (tumor necrosis factor) therapies. It works by binding to and neutralizing TNF-alpha, a substance in the body that causes inflammation.
   • A treatment for autoimmune diseases: It is specifically used to manage symptoms and induce remission in certain chronic inflammatory conditions.

Usage Examples

• Noun:
  • The doctor prescribed infliximab to control the patient's rheumatoid arthritis.
  • Infliximab is administered via intravenous infusion over a period of several hours.
  • Patients receiving infliximab require regular monitoring for potential side effects.

Advanced Usage

• "to be on infliximab therapy": to be undergoing treatment with this medication.

  • After failing other treatments, she has been on infliximab therapy for six months.

• "infliximab infusion": refers to the process of receiving the drug intravenously.

  • He goes to the clinic every eight weeks for his scheduled infliximab infusion.

Variants and Related Words

• Remicade (n): The primary trade name for infliximab.

  • Remicade is a well-known brand of infliximab.

• Anti-TNF agent (n): The class of drugs to which infliximab belongs.

  • Infliximab is a potent anti-TNF agent used for severe inflammation.

• Biologic (n): A broader category of drugs derived from living organisms, which includes infliximab.

  • As a biologic, infliximab requires special handling and storage.

Synonyms

• Monoclonal antibody: A type of protein made in the laboratory that can bind to specific targets in the body, describing the mechanism of infliximab.
• Immunosuppressant: A substance that reduces the activation or efficacy of the immune system, which is a general effect of infliximab.

Related Phrases

• "response to infliximab": refers to how well a patient's condition improves with the treatment.

  • The patient showed a positive response to infliximab, with reduced joint swelling.

• "infliximab dosage": refers to the specific amount and schedule of the medication prescribed.

  • The physician adjusted the infliximab dosage based on the patient's weight and disease activity.

Noun

1. an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis
2. a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician