irritate

/'iriteit/
Verb
  1. excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus
    • irritate the glands of a leaf
  2. excite to an abnormal condition, or chafe or inflame
    • Aspirin irritates my stomach
  3. cause annoyance in; disturb, especially by minor irritations
    • Mosquitoes buzzing in my ear really bothers me
    • It irritates me that she never closes the door after she leaves

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irritate
The loud noise began to irritate the sleeping cat.