lymphoblast

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lymphoblast

A scientist examines a lymphoblast under a microscope.

Definition

Noun: * An immature lymphocyte: A lymphoblast is a large, immature cell found in the bone marrow and lymphatic tissues. It is the precursor cell that develops into a mature lymphocyte, which is a type of white blood cell crucial for the body's immune response.

Usage

The term "lymphoblast" is a specialized medical and biological term. It is primarily used in clinical, laboratory, and academic contexts to describe a specific stage in blood cell development. * It functions as a countable noun (e.g., a lymphoblast, the lymphoblasts, many lymphoblasts). * It is often discussed in contrast to its mature form, the "lymphocyte."

Examples
  • In a laboratory report: "The bone marrow biopsy showed an increased number of lymphoblasts."
  • In a textbook: "A lymphoblast undergoes several divisions before maturing into a functional T cell or B cell."
  • In a diagnosis: "The presence of over 20% lymphoblasts in the peripheral blood is a key diagnostic criterion for acute lymphoblastic leukemia (ALL)."
Advanced Usage
  • In Oncology: The abnormal, rapid proliferation of lymphoblasts is the hallmark of acute lymphoblastic leukemia (ALL), a type of cancer of the blood and bone marrow.
  • Morphology: In cytology, a lymphoblast is characterized by a large nucleus with fine chromatin, one or more nucleoli, and a small amount of basophilic cytoplasm.
Variants and Related Words
  • Lymphoblastic (adjective): Pertaining to or resembling a lymphoblast.
    • Example: "She was diagnosed with lymphoblastic lymphoma."
  • Lymphocyte (noun): The mature form of the cell into which a lymphoblast develops.
  • Blast Cell (noun): A general term for an immature precursor cell; a lymphoblast is a type of blast cell.
Synonyms
  • Immature lymphocyte: This is a descriptive synonym that directly explains the term.
  • Lymphoid precursor cell: A more technical synonym used in cellular biology.
Notes on Meaning

The word "lymphoblast" has a single, precise meaning in hematology and immunology. It does not have idiomatic or figurative uses. Its definition is consistent across medical and scientific English.

lymphoblast

A scientist examines a lymphoblast under a microscope.

Noun
  1. an immature lymphocyte

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