midazolam
Học thuậtThân thiện
Definition
Noun A short-acting benzodiazepine derivative, used medically as a sedative, anxiolytic, and amnestic agent, often administered intravenously before medical procedures.
Usage
Midazolam is used as a medical drug. It is primarily administered by healthcare professionals in clinical settings. - It is used for sedation (to calm a patient and reduce anxiety). - It is used for procedural sedation (to help patients tolerate uncomfortable medical or dental procedures). - It is used for induction of anesthesia (to begin the process of general anesthesia). - It is used for its amnestic effects (to impair memory of the procedure).
Examples
- The anesthesiologist administered midazolam to sedate the patient before the endoscopy.
- A small dose of midazolam is often given to reduce a patient's anxiety prior to surgery.
- Due to its rapid onset, midazolam is commonly used for sedation in emergency departments.
- The dentist used midazolam for conscious sedation during the wisdom tooth extraction.
Advanced Usage
- Conscious sedation: A state of minimally depressed consciousness where the patient can respond to verbal commands. is a common agent for achieving this state.
- Premedication: is frequently used as a premedication agent before surgery to produce sedation, relieve anxiety, and provide anterograde amnesia.
- Status epilepticus: In emergency medicine, can be used intramuscularly as a first-line treatment for seizures that do not stop (status epilepticus), especially when intravenous access is difficult.
Variants and Related Words
- Benzodiazepine (noun): The class of psychoactive drugs to which midazolam belongs. Other examples include diazepam and lorazepam.
- Sedative (noun/adjective): A substance that induces sedation; having a calming or sleep-inducing effect.
- Anxiolytic (noun/adjective): A drug that reduces anxiety; anxiety-reducing.
- Hypnotic (noun/adjective): A drug that induces sleep; sleep-inducing.
- Versed® (noun): A common trade name for midazolam in some countries.
Synonyms
- Sedative
- Anxiolytic
- Premedication agent
- (Trade Name) Versed®
Important Notes
- Not a standalone pain reliever: While reduces anxiety and memory of pain, it is not an analgesic (pain reliever). It is often co-administered with pain medication like fentanyl.
- Controlled substance: is a prescription-only medication and a controlled substance due to its potential for dependence and abuse.
- Route of administration: While often injected (intravenous, intramuscular), it can also be given orally or nasally, especially in pediatric settings.
Noun
- an injectable form of benzodiazepine (trade name Versed) useful for sedation and for reducing pain during uncomfortable medical procedures