nephroblastoma

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Thân thiện
Definition

Noun: A malignant (cancerous) kidney tumor that primarily occurs in young children. It is characterized by symptoms including high blood pressure (hypertension), blood in the urine (hematuria), and the presence of a mass that can be felt during a physical examination.

Usage
  • This is a highly specific medical term used in oncology (the study of cancer) and pediatrics (the branch of medicine dealing with children).
  • It is used formally by healthcare professionals in diagnoses, medical literature, and clinical discussions.
  • Example: "The pediatric oncologist confirmed the diagnosis of nephroblastoma after reviewing the biopsy results and imaging scans."
Examples
  • "Early detection of a nephroblastoma significantly improves the prognosis for the child."
  • "The standard treatment protocol for nephroblastoma often involves a combination of surgery and chemotherapy."
  • "Research into the genetic factors associated with nephroblastoma is ongoing."
Advanced Usage
  • In Medical Staging: The term is used in the context of staging the cancer's progression (e.g., Stage I to Stage V nephroblastoma), which determines the treatment plan.
  • In Differential Diagnosis: Doctors use it when distinguishing this tumor from other abdominal masses or renal cancers in children, such as clear cell sarcoma or rhabdoid tumor.
Variants and Related Words
  • Wilms' tumor: This is the most common and widely used synonym for nephroblastoma, named after Dr. Max Wilms. The terms are often used interchangeably in clinical practice.
  • Pediatric renal tumor: A more general descriptive term.
  • Adenomyosarcoma (archaic): An older, less common name for this tumor.
Synonyms
  • Wilms' tumor
  • Wilms tumor (alternative spelling without the apostrophe 's')
Notes on Meaning
  • The definition provided specifies the core characteristics: it is a malignant renal tumor (kidney cancer) of young children with the classic triad of hypertension, hematuria, and a palpable mass. However, not all three symptoms are always present in every case.
Noun
  1. malignant renal tumor of young children characterized by hypertension and blood in the urine and the presence of a palpable mass

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