Definition

1. Noun:
   • A uricosuric drug: "probenecid" is a specific pharmaceutical agent belonging to the class of uricosuric drugs. Its primary function is to increase the excretion of uric acid through the kidneys.
   • A treatment for gout: "probenecid" is used therapeutically to manage gout by lowering the concentration of uric acid in the bloodstream, thereby helping to prevent the formation of urate crystals and gout attacks.

Usage Examples

• Noun:
  • The doctor prescribed probenecid to manage his chronic gout.
  • Probenecid works by inhibiting the reabsorption of uric acid in the kidneys.

Advanced Usage

• In combination therapy: "probenecid" is sometimes used to enhance the effectiveness of other drugs, particularly certain antibiotics, by delaying their renal excretion.
  • Probenecid is administered concurrently with some penicillin antibiotics to maintain higher blood levels.

Variants and Related Words

• Uricosuric (adj/n): Describing a substance or referring to a drug that promotes the excretion of uric acid in the urine. Probenecid is a prototypical uricosuric agent.

Synonyms

• Uricosuric agent: A general term for drugs that increase uric acid excretion.
• Gout medication: A broader category of pharmaceuticals used to treat gout, which includes probenecid.

Related Terms (Note: "probenecid" itself does not form phrasal verbs or idioms)

• Hyperuricemia: The medical condition of high uric acid levels in the blood, which probenecid helps to treat.
• Renal excretion: The process of elimination through the kidneys, which probenecid affects for uric acid.

Noun

1. a uricosuric drug that reduces the level of uric acid in the blood; used to treat gout