pyocyanase

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pyocyanase

A scientist examines a sample of pyocyanase under a laboratory light.

Definition

Noun: A yellow-green mixture of antibiotics obtained from the bacillus of green pus (Pseudomonas aeruginosa). It was one of the first commercially available antibiotic preparations.

Usage
  • Pyocyanase is used as a historical term in medicine and microbiology. It refers specifically to the early antimicrobial substance derived from cultures.
  • It is typically used in academic or historical contexts when discussing the history of antibiotics.
Examples
  • The discovery of pyocyanase in the late 19th century preceded the widespread use of penicillin.
  • Early studies on pyocyanase provided important insights into bacterial antagonism.
  • Due to its toxicity and instability, pyocyanase was not a successful therapeutic agent.
Advanced Usage
  • The term is primarily used in historical discourse. For example: "The era of antibiotic therapy can be traced back to substances like pyocyanase."
  • It may appear in scientific literature reviewing the evolution of antimicrobial drugs.
Variants and Related Words
  • Pyocyanin (noun): A blue-green phenazine pigment produced by , which is a component of the mixture historically called pyocyanase. It has antimicrobial properties itself.
  • Antibiotic (noun): A more general term for a substance produced by a microorganism that inhibits the growth of other microorganisms.
Synonyms
  • Early antibiotic preparation
  • Historical antimicrobial mixture
Notes on Meaning

This word has a very specific and narrow meaning. It does not refer to modern, purified antibiotics. Its use is almost exclusively confined to discussions about the history of medicine and microbiology.

pyocyanase

A scientist examines a sample of pyocyanase under a laboratory light.

Noun
  1. a yellow-green mixture of antibiotics obtained from the bacillus of green pus