pyrophosphate
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Definition
- Noun:
- A salt or ester of pyrophosphoric acid: A chemical compound containing the pyrophosphate ion (P₂O₇⁴⁻), which consists of two phosphate groups linked together. It is involved in various biochemical energy transfer processes.
Examples of Usage
- Noun:
- Adenosine triphosphate (ATP) is hydrolyzed to adenosine monophosphate and pyrophosphate.
- The enzyme catalyzes the release of pyrophosphate from the nucleotide substrate.
- Calcium pyrophosphate crystals can deposit in joints, causing inflammation.
Advanced Usage
- "Inorganic pyrophosphate (PPi)": This specific term refers to the free ion (P₂O₇⁴⁻) in biological systems, often a byproduct of biosynthetic reactions like DNA and protein synthesis.
- Inorganic pyrophosphate is hydrolyzed by pyrophosphatase to orthophosphate, driving reactions forward.
Variants and Related Words
- Pyrophosphoric acid (n): The parent acid (H₄P₂O₇) from which pyrophosphate salts and esters are derived.
- Pyrophosphatase (n): An enzyme that catalyzes the hydrolysis of pyrophosphate into two phosphate ions.
- Diphosphate (n): A synonym often used interchangeably with pyrophosphate in biochemical contexts, especially for organic esters (e.g., adenosine diphosphate, ADP).
Synonyms
- Diphosphate: (In biochemistry, particularly for esters) A compound containing two phosphate groups.
- PPi: A common abbreviation for inorganic pyrophosphate.
Related Phrases
- Pyrophosphate bond: Refers to the high-energy phosphoanhydride bond linking the two phosphate groups in the pyrophosphate molecule.
- The hydrolysis of the pyrophosphate bond releases significant energy.
Noun
- a salt or ester of pyrophosphoric acid