quinacrine
Definition
Noun: 1. A synthetic medicinal compound: Quinacrine is a yellow, crystalline powder used as an antimalarial and anthelmintic (anti-worm) drug. It is known for its distinctive bitter taste and its ability to cause a yellow discoloration of the skin and eyes.
Usage
- Quinacrine is administered orally, typically in tablet form.
- It is used to treat specific parasitic infections.
Examples
- Noun:
- The doctor prescribed quinacrine to treat the patient's giardiasis.
- Quinacrine was widely used by soldiers during World War II for malaria prophylaxis.
- A side effect of long-term quinacrine use is a reversible yellowing of the skin.
Advanced Usage
- Historical Context: Quinacrine (mepacrine) was a primary antimalarial drug before the development of chloroquine and other modern therapies. Its use declined due to side effects and the availability of more effective drugs.
- Other Medical Uses: Beyond its original indications, quinacrine has been investigated for other purposes, such as a sclerosing agent in certain medical procedures.
Variants and Related Words
- Mepacrine: The British Approved Name (BAN) for quinacrine.
- Atabrine: A former prominent trade name for quinacrine hydrochloride.
- Acanridine: A related chemical name sometimes referenced.
Synonyms
- Mepacrine (pharmaceutical synonym)
- Atebrin (alternative spelling/variant)
Notes
- Quinacrine is primarily of historical and specific medical interest today. It is not a first-line treatment for malaria in modern medicine.
- The term is almost exclusively used in medical, pharmacological, and historical contexts.
Noun
-
a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
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