ruination

/rui'neiʃn/
Noun
  1. destruction achieved by causing something to be wrecked or ruined
  2. failure that results in a loss of position or reputation
  3. an event that results in destruction
  4. an irrecoverable state of devastation and destruction
    • you have brought ruin on this entire family

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ruination
The reckless gambler faced the ruination of his family's fortune.