sucralfate
Definition
Noun A medication used to treat and prevent the recurrence of duodenal ulcers. It works by forming a protective coating over the ulcer site, shielding it from stomach acid and digestive enzymes to promote healing.
Usage
"Sucralfate" is used as a non-systemic, prescription gastrointestinal agent. It is typically taken orally, on an empty stomach. * The doctor prescribed sucralfate to coat the ulcer and allow it to heal. * Sucralfate therapy requires taking the medication several times a day.
Advanced Usage
- Mechanism of Action: Sucralfate is described as a locally acting cytoprotective agent. It binds to proteins at the ulcer crater to form a physical barrier.
- Administration: It is crucial that sucralfate is taken separately from other medications (typically one hour before or two hours after) as it can bind to and reduce the absorption of many drugs.
Variants and Related Words
- Carafate: A common trade name for sucralfate.
- Antipeptic: A descriptive term sometimes associated with its function of inhibiting the action of pepsin.
- Gastroprotective Agent: A class of drugs that includes sucralfate.
Synonyms
- Ulcer-coating agent
- Gastroprotective medication
Related Phrases
- To be on sucralfate: To be undergoing treatment with this medication.
- The patient was on sucralfate for eight weeks.
- Sucralfate slurry: A suspension of crushed sucralfate tablets in water, sometimes used for topical application or for patients who have difficulty swallowing.
- The nurse prepared a sucralfate slurry for the patient with esophagitis.
Noun
-
medicine consisting of a tablet (trade name Carafate) used to treat peptic ulcers; said to bind to the ulcer site and coat it
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