transubstantiate

/,trænsəb'stænʃieit/
Verb
  1. change or alter in form, appearance, or nature
    • This experience transformed her completely
    • She transformed the clay into a beautiful sculpture
    • transubstantiate one element into another
  2. change (the Eucharist bread and wine) into the body and blood of Christ

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transubstantiate
The alchemist sought to transubstantiate lead into gold.