antagonism

/æn'tægənizm/
Noun
  1. (biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure
  2. an actively expressed feeling of dislike and hostility
  3. the relation between opposing principles or forces or factors
    • the inherent antagonism of capitalism and socialism
  4. a state of deep-seated ill-will

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antagonism
A specific drug molecule can block a receptor by binding to it and causing antagonism.