cytosine

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cytosine

A scientist points to a diagram showing cytosine pairing with guanine.

Definition
  1. Noun:
    • A nitrogenous base found in DNA and RNA: Cytosine is one of the four main nucleobases present in the nucleic acids DNA and RNA. It is a pyrimidine derivative.
    • A component of nucleotides: In DNA and RNA, cytosine pairs specifically with guanine through hydrogen bonding, forming one of the fundamental base pairs that encode genetic information.
Usage Examples
  • Noun:
    • The sequence of adenine, thymine, cytosine, and guanine determines our genetic code.
    • A point mutation changed the cytosine in the DNA strand to a thymine.
Advanced Usage
  • "Cytosine methylation": A biochemical process where a methyl group is added to a cytosine nucleotide, often involved in regulating gene expression.
    • Cytosine methylation is a key epigenetic mechanism.
Variants and Related Words
  • Deoxycytidine (n): The nucleoside form of cytosine when linked to deoxyribose, as found in DNA.
  • Cytidine (n): The nucleoside form of cytosine when linked to ribose, as found in RNA.
  • Cytosine arabinoside (n): A chemotherapy medication that is a synthetic nucleoside analogue of cytosine.
Synonyms
  • C (n): The standard single-letter abbreviation for cytosine in genetic sequences.
  • Pyrimidine base (n): A broader category of nitrogenous bases to which cytosine belongs.
Related Phrases and Compounds
  • Cytosine-guanine pair (C-G pair) (n): The specific pairing between cytosine and guanine in a DNA double helix.
    • The stability of a DNA region depends on the number of cytosine-guanine pairs.
  • Cytosine deamination (n): A chemical reaction in which cytosine is converted to uracil, which can lead to a mutation if not repaired.
    • Cytosine deamination is a common type of DNA damage.
cytosine

A scientist points to a diagram showing cytosine pairing with guanine.

Noun
  1. a base found in DNA and RNA and derived from pyrimidine; pairs with guanine

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