deamination

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deamination

A scientist observes the deamination process in a laboratory diagram.

Definition
  1. Noun:
    • The removal of an amino group from an amino acid or another amino compound: This is a biochemical process where an amino group (-NH₂) is removed from a molecule, often as part of protein metabolism.
Usage Examples
  • Noun:
    • Deamination is a crucial step in the breakdown of amino acids in the liver.
    • The enzyme catalyzes the deamination of glutamate, producing alpha-ketoglutarate and ammonia.
Advanced Usage
  • Oxidative deamination: A specific type of deamination that involves oxidation, often producing ammonia and a keto acid.
    • Oxidative deamination is primarily carried out by glutamate dehydrogenase.
Variants and Related Words
  • Deaminate (verb): To remove an amino group from a compound.
    • The liver can deaminate excess amino acids.
  • Deaminase (noun): An enzyme that catalyzes a deamination reaction.
    • Adenosine deaminase deficiency can cause severe health problems.
Synonyms
  • Deaminization (noun): A less common synonym for deamination.
Related Phrases and Concepts
  • Urea cycle: A metabolic pathway that processes the ammonia produced from deamination.
    • The ammonia generated by deamination is converted to urea in the urea cycle.
deamination

A scientist observes the deamination process in a laboratory diagram.

Noun
  1. removal of the amino radical from an amino acid or other amino compound

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