deamination
Definition
- Noun:
- The removal of an amino group from an amino acid or another amino compound: This is a biochemical process where an amino group (-NH₂) is removed from a molecule, often as part of protein metabolism.
Usage Examples
- Noun:
- Deamination is a crucial step in the breakdown of amino acids in the liver.
- The enzyme catalyzes the deamination of glutamate, producing alpha-ketoglutarate and ammonia.
Advanced Usage
- Oxidative deamination: A specific type of deamination that involves oxidation, often producing ammonia and a keto acid.
- Oxidative deamination is primarily carried out by glutamate dehydrogenase.
Variants and Related Words
- Deaminate (verb): To remove an amino group from a compound.
- The liver can deaminate excess amino acids.
- Deaminase (noun): An enzyme that catalyzes a deamination reaction.
- Adenosine deaminase deficiency can cause severe health problems.
Synonyms
- Deaminization (noun): A less common synonym for deamination.
Related Phrases and Concepts
- Urea cycle: A metabolic pathway that processes the ammonia produced from deamination.
- The ammonia generated by deamination is converted to urea in the urea cycle.
Noun
-
removal of the amino radical from an amino acid or other amino compound
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