deficiency

/di'fiʃənsi/
Noun
  1. lack of an adequate quantity or number
    • the inadequacy of unemployment benefits
  2. the state of needing something that is absent or unavailable
    • there is a serious lack of insight into the problem
    • water is the critical deficiency in desert regions
    • for want of a nail the shoe was lost

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deficiency
A child has a vitamin deficiency that causes fatigue.