hyperparathyroidism
Học thuậtThân thiện
Definition
- Noun:
- A medical condition involving excessive secretion of parathyroid hormone: Hyperparathyroidism is a disorder characterized by the overactivity of the parathyroid glands, leading to the production of too much parathyroid hormone (PTH).
- A cause of abnormally high blood calcium levels: This condition results in hypercalcemia, which is an elevated level of calcium in the blood.
- A disorder affecting multiple body systems: The excess calcium can impact various organs and systems, notably causing bone weakening through resorption and contributing to osteoporosis.
Usage Examples
- Noun:
- The patient was diagnosed with primary hyperparathyroidism after routine blood tests revealed high calcium levels.
- Symptoms of hyperparathyroidism can include fatigue, kidney stones, and bone pain.
- Treatment for hyperparathyroidism may involve surgical removal of the overactive gland.
Advanced Usage
- "Primary hyperparathyroidism": The most common form, where one or more parathyroid glands are enlarged and overproduce hormone independently, often due to a benign tumor (adenoma).
- Primary hyperparathyroidism is frequently discovered incidentally during blood work for other reasons.
- "Secondary hyperparathyroidism": A condition where the parathyroid glands become overactive in response to low blood calcium levels, often due to kidney failure or severe vitamin D deficiency.
- Secondary hyperparathyroidism is a common complication of chronic kidney disease.
- "Tertiary hyperparathyroidism": A state of autonomous parathyroid hormone overproduction that can develop after long-standing secondary hyperparathyroidism, even if the original trigger is corrected.
- After a kidney transplant, some patients develop tertiary hyperparathyroidism.
Variants and Related Words
- Hyperparathyroid (adj): Pertaining to or affected by hyperparathyroidism.
- The patient had hyperparathyroid bone disease.
- Parathyroidectomy (n): The surgical removal of one or more parathyroid glands, a common treatment for hyperparathyroidism.
- The surgeon performed a parathyroidectomy to treat the hyperparathyroidism.
Synonyms
- Parathyroid overactivity: A descriptive synonym for the condition.
- PTH excess: A biochemical term referring to the elevated hormone level central to the disorder.
Related Phrases
- "Hypercalcemia of hyperparathyroidism": A phrase specifying the high blood calcium resulting from this condition.
- The hypercalcemia of hyperparathyroidism requires careful management.
- "Bone resorption in hyperparathyroidism": A phrase describing a key pathological effect of the disease.
- The X-ray showed significant bone resorption in hyperparathyroidism.
Noun
- excessive secretion of parathyroid hormone resulting in abnormally high levels of calcium in the blood; can affect many systems of the body (especially causing bone resorption and osteoporosis)