Definition

Noun: A chemical compound characterized by the presence of the functional group -C=NOH, formed by the condensation of a carbonyl compound (such as an aldehyde or ketone) with hydroxylamine.

Usage

An oxime is a specific type of organic compound. The term is used primarily in chemistry to classify and describe molecules with this defining structural feature. It is a countable noun (e.g., an oxime, several oximes).

Examples

• The chemist synthesized a new oxime in the laboratory.
• Acetone oxime is a common example of a ketone-derived oxime.
• These oximes are being studied for their potential pharmaceutical applications.

Advanced Usage

• Stereochemistry: Oximes can exist as stereoisomers (syn and anti isomers) due to the lack of free rotation around the C=N bond.
  • The two geometric isomers of the oxime were separated using chromatography.
• Functional Group Transformation: Oximes are important intermediates in organic synthesis and can be converted into other functional groups, such as amines (via the Beckmann rearrangement).
  • The oxime was subjected to Beckmann rearrangement conditions to yield the corresponding amide.

Variants and Related Words

• Aldoxime (n): An oxime derived specifically from an aldehyde (R-CH=NOH).
• Ketoxime (n): An oxime derived specifically from a ketone (R₂C=NOH).
• Oximate (n): The conjugate base of an oxime, formed by deprotonation of the hydroxyl group.

Synonyms

• There are no direct common-language synonyms. In technical contexts, it may be described as a "hydroxylimine" or by its structural formula .

Related Phrases

• Form an oxime: To undergo a chemical reaction to produce an oxime.
  • The ketone will form an oxime when treated with hydroxylamine hydrochloride.
• Oxime derivative: A compound that is structurally based on or modified from an oxime.
  • The drug is an oxime derivative designed to reactivate the enzyme.

Noun

1. any compound containing the group -C=NOH