pestilence

/'pestiləns/
Noun
  1. a pernicious and malign influence that is hard to get rid of
    • racism is a pestilence at the heart of the nation
    • according to him, I was the canker in their midst
  2. any epidemic disease with a high death rate
  3. a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal

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pestilence
A medieval village suffers from a terrible pestilence.