ultracentrifugation

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ultracentrifugation

The scientist uses ultracentrifugation to separate the sample components.

Definition
  1. Noun:
    • Centrifugation at very high speeds: A process of separating particles from a solution by subjecting it to an extremely high centrifugal force, achieved by spinning at exceptionally high rotational speeds.
Usage Examples
  • Noun:
    • The isolation of ribosomes requires ultracentrifugation.
    • Ultracentrifugation is a key technique in purifying viral particles for study.
Advanced Usage
  • Analytical ultracentrifugation: A specific application used to study the properties of macromolecules, such as their mass, shape, and interaction, in solution during the high-speed spinning process.

    • The research team used analytical ultracentrifugation to determine the protein's molecular weight.
  • Preparative ultracentrifugation: The use of the technique to physically isolate and purify specific biological components, like organelles or nucleic acids.

    • The mitochondrial fraction was obtained through preparative ultracentrifugation.
Variants and Related Words
  • Ultracentrifuge (n): The high-speed centrifuge machine used to perform ultracentrifugation.

    • The sample was placed in the ultracentrifuge for two hours.
  • Ultracentrifugal (adj): Relating to or involving ultracentrifugation.

    • The ultracentrifugal force achieved was over 500,000 g.
Synonyms
  • High-speed centrifugation
  • High-g-force separation
Related Phrases
  • To subject to ultracentrifugation: The act of processing a sample using this technique.
    • The cell lysate was subjected to ultracentrifugation to pellet the membranes.
ultracentrifugation

The scientist uses ultracentrifugation to separate the sample components.

Noun
  1. centrifugation at very high speeds