SSRI

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Definition

Noun: * A type of antidepressant medication. SSRIs work by increasing the level of serotonin, a natural substance in the brain that helps maintain mental balance, by preventing nerve cells from reabsorbing it.

Examples
  • Noun:
    • Her doctor prescribed an SSRI to help manage her anxiety and depression.
    • Fluoxetine was the first SSRI approved for clinical use.
    • Common side effects of SSRIs can include nausea and headaches.
Advanced Usage
  • Therapeutic Use: The term is primarily used in medical, psychiatric, and pharmacological contexts to describe a specific class of psychoactive drugs.
    • The study compared the efficacy of an SSRI with a tricyclic antidepressant.
  • Mechanism of Action: Often explained by its full name, "selective serotonin reuptake inhibitor," to describe how it functions.
    • As an SSRI, it selectively inhibits the reuptake of serotonin in the synaptic cleft.
Variants and Related Words
  • Selective Serotonin Reuptake Inhibitor (n): The full, technical name for an SSRI.
    • "SSRI" is an acronym for selective serotonin reuptake inhibitor.
  • SNRI (n): Serotonin-Norepinephrine Reuptake Inhibitor; a related but distinct class of antidepressants that affect two neurotransmitters.
  • Antidepressant (n): The broader category of drugs to which SSRIs belong.
Synonyms
  • Serotonin reuptake inhibitor: A more descriptive synonym, though less commonly used than the acronym.
  • Antidepressant: A broader, more general term. (Note: Not all antidepressants are SSRIs, but all SSRIs are antidepressants.)
Related Phrases
  • On an SSRI: A common phrase describing a patient's medication regimen.
    • She has been on an SSRI for six months and reports feeling much better.
  • SSRI treatment: Refers to the therapeutic use of this drug class.
    • The guidelines recommend SSRI treatment as a first-line intervention for major depressive disorder.
Noun
  1. an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

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