amyloid

/'æmilɔid/
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amyloid

Amyloid deposits can be seen under the microscope in certain medical conditions.

Definition
  1. Adjective:

    • Resembling starch: Having a physical or chemical similarity to starch, often used in scientific contexts to describe substances or structures.
  2. Noun:

    • (Pathology) A waxy, translucent complex protein: An abnormal, insoluble protein that accumulates in tissues during certain diseases, resembling starch in some of its properties.
    • A non-nitrogenous food substance consisting chiefly of starch: (Less common, historical usage) Any starchy substance or a substance resembling starch.
Examples of Usage
  • Adjective:

    • The biopsy revealed amyloid deposits in the organ. (The biopsy showed deposits resembling starch in the organ.)
    • Under the microscope, the material had an amyloid appearance. (Under the microscope, the material had an appearance similar to starch.)
  • Noun (Pathological):

    • Alzheimer's disease is associated with the formation of amyloid in the brain. (Alzheimer's disease is connected to the formation of this waxy protein in the brain.)
    • The doctor identified the substance as amyloid. (The doctor identified the substance as the abnormal protein.)
  • Noun (Historical/Biochemical):

    • Older texts sometimes refer to starchy foods as amyloid. (Older texts sometimes call starchy foods by this term.)
Advanced Usage
  • "Amyloid plaque": A specific cluster or deposit of the abnormal amyloid protein, often in the brain.

    • Researchers are studying how to clear amyloid plaques. (Researchers are studying how to remove these protein clusters.)
  • "Amyloidosis": A group of diseases characterized by the buildup of amyloid proteins in various organs.

    • He was diagnosed with systemic amyloidosis. (He was diagnosed with the disease where amyloid builds up throughout the body's systems.)
Variants and Related Words
  • Amyloidogenic (adj): Having the potential to form amyloid.

    • The scientist studied the amyloidogenic properties of the peptide. (The scientist studied the peptide's properties that could lead to amyloid formation.)
  • Amyloid precursor protein (APP): A protein from which amyloid peptides can be derived.

    • Mutations in the gene for APP can lead to amyloid production. (Changes in the gene for this precursor protein can cause amyloid to be made.)
Synonyms
  • Starchlike (adj): Resembling starch (for the adjective form).
  • Amylaceous (adj): Having the nature of starch.
Related Phrases
  • "Amyloid beta" (Aβ or Abeta): A specific peptide that forms the amyloid plaques found in the brains of Alzheimer's patients.

    • The drug aims to reduce levels of amyloid beta. (The drug aims to lower the amount of this specific peptide.)
  • "Amyloid fibril": The insoluble, fibrous structure formed by aggregated amyloid proteins.

    • The stability of amyloid fibrils makes them difficult to break down. (The strength of these fibrous structures makes them hard to destroy.)
amyloid

Amyloid deposits can be seen under the microscope in certain medical conditions.

Adjective
  1. resembling starch
Noun
  1. (pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue
  2. a non-nitrogenous food substance consisting chiefly of starch; any substance resembling starch