hub

/hʌb/
Noun
  1. a center of activity or interest or commerce or transportation; a focal point around which events revolve
    • the playground is the hub of parental supervision
    • the airport is the economic hub of the area
  2. the central part of a car wheel (or fan or propeller etc) through which the shaft or axle passes

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hub
The airport is the economic hub of the region.